I was wondering if anybody could help me with the following question. I am trying to figure out how to determine two things:
- Level of significance between pre op and post-op CKD (kidney function)
- Level of significance between pre op and post-op for median of eGFR and creatinine (also kidney function),
To help you understand, people either undergo a treatment RN or a treatment PN.
I hope I made myself clear, I am struggling for days now so I was hoping somebody could give me a clue. Thanks in advance!
| RN | PN | |||||
| Pre-op | 1 year Post-op | p-value | Pre-op | 1 year Post-op | p-value | |
| CKD stage n (%) | ??? | ??? | ||||
| 1 (<15) | 0 | 0 | 0 | 0 | ||
| 2 (15 – 29) | 0 | 1 | 0 | 0 | ||
| 3a (30 – 44) | 3 | 20 | 8 | 8 | ||
| 3b (45 – 59) | 11 | 30 | 5 | 11 | ||
| 4 (60 – 89) | 50 | 27 | 51 | 45 | ||
| 5 (>90) | 36 | 3 | 36 | 12 | ||
| eGFR (ml/min/1.73 m2) median [IQR] | 83 (69 – 95) | 57 (44 – 65) | ??? | 79 (71 – 94) | 73 (60 – 87) | ??? |
| Creatinine median [IQR] | 81 (69 – 92) | 107 (92 – 127) | ??? | 84 (72 – 95) | 88 (73 – 104) | ??? |
| New-onset CKD n (%) | 42 | 11 | <0.05 | |||
| Negative delta-eGFR (%) | 33 (23 – 40) | 11 (3 – 19) | <0.05 | |||
| Negative delta-eGFR median [IQR] | 28 (18 – 34) | 8 ( 2 – 16) | <0.05 | |||
| Delta serum creatinine (%) | 27 (4 – 46) | 10 (-34 – 17) | <0.05 | |||
| Delta serum creatinine median [IQR] | 32 (22 – 41) | 8 ( 1 – 16) | <0.05 | |||
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