I use . cutpt to calculate cut points (reference ranges) for laboratory diagnostic methods. My outcome (classvar) is continuous (concentration in pg/mL). In one case I am getting very discrepant results of the AUC after . cutpt and . roctab. They are here:
Code:
. cutpt c1 ov Empirical cutpoint estimation Method: Liu Reference variable: c1 (0=neg, 1=pos) Classification variable: ov Empirical optimal cutpoint: 571.5 Sensitivity at cutpoint: 0.94 Specificity at cutpoint: 0.78 Area under ROC curve at cutpoint: 0.86
Code:
. roctab c1 ov ROC -Asymptotic Normal-- Obs Area Std. Err. [95% Conf. Interval] ------------------------------------------------------------ 133 0.9282 0.0210 0.88708 0.96929
(1) Is there any explanation for this discrepancy?
(2) What does it actually mean "Area under ROC curve at cutpoint"? To my understanding there is not such thing as AUC at cutpoint; AUC is one and the same for all points.
Thank you in advance for commenting.
Best,
Piotr Lewczuk
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