My name is Hatem Ali
I am trying to do meta analysis of hazard ratio to assess effect of rise in IL6 on overall survival
I have the following data
id | Sample size | p value | CI LOWER | CI HIGHER | notes |
Pecoits-Filho (HR for overall mortality,IL6 was higher in CVD group) | 99 | 0.01 | chi square=11.3 | ||
Liu et al | 50 | 0.001 | OR=6.9 | ||
cho et al (trend over time) | 175 | 0.03 | 1.31 | 87.75 | OR=10.72 |
Lambie et al | 575 | 0.008 | 1.22 | 3.78 | HR=2.15 |
Lambie et al 2 | 384 | 0.009 | 1.28 | 5.58 | HR=2.68 |
Wang et al(mortality and Coronary calcification) | 152 | 0.003 | 1.53 | 8.26 | HR=3.56 |
As you see, I have sample size, p value, lower and higher confidence interval.
However, only 3 studies are reporting HR, 2 are reporting OR, one is reporting chi square.
Is there a way to calculate hazard ratio from the studies reporting odds ratio or chi square?
In other words,can I convert Odds ratio to hazard ratio? and can I convert chi square to hazard ratio?
If that is not possible, then , can I calculate Relative risk for each study from the data I have?
Can I calculate RR from HR, 95% CI , sample size and P value?
Can I calculate RR drom OR, 95%CI, sample size and P value?
Can I calculate RR from chi square, sample size and P value?
Finally , after calculating HR, the syntax to use is : metan HR lower higher, counts random
is that correct?
How can I add the name of the studies to the forest plot using this syntax?
Looking forward to hear back from you
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